1 Series
The Xelair® 1 Series are analyst workstations. They automate individual stages of dose content uniformity testing.
3 Series
The Xelair® 3 Series are semi-automated platforms. They automate the entire through life testing of an inhaler device.
5 Series
The Xelair® 5 Series are fully automated systems. They offer 24/7 unattended operation.
DCU Evaluation kit
Manual test apparatus is available for evaluation, method development and routine laboratory use on a commercial loan or purchase basis. The apparatus uses the core technology at the heart of the Xelair® range. Methods developed using the manual apparatus can be transferred onto any platform in the Xelair® range.
Uses Astech core technology for dose collection and dose recovery operations
| Product name | Xelair® 1 Series | Xelair® 3 Series | Xelair® 5 Series |
| Description | Analyst workstations | Semi automated platforms | Full automated systems – 24/7 unattended operation |
| Core Technology | Uses Astech core technology for dose collection or dose recovery operations | Uses Astech core technology for dose collection and dose recovery operations | |
| MDI/BAI/DPI configurations available | Yes | Yes | Yes |
| Inhaler Shaking | Yes, a number of shake profiles are available including linear shaking, rotary shaking and arc inversion shaking. Frequencies up to 6 Hz with “true” user configurable profile generation and profile monitoring | ||
| Readily adapted to any inhaler type | Yes, actuation mechanisms and shakers can be supplied to suit any inhaler type | ||
| Automated waste fire sequences | A Xelair® 1 series workstation is available for waste firing and dose collection including sonic flow confirmation | Allows execution of pre-approved sequences for waste firing. Dose collections can be scheduled anywhere in the sequence. | |
| Automated dose collection | Automated dose collection into Astech’s collection chamber. Single shot or multiple shot configurable via the method. | Automated dose collection into Astech’s collection chamber. Single shot or multiple shot configurable via the method. | |
| Automated control of vacuum flow rate | Yes | Yes | |
| Sonic flow confirmation (P2 & P3) | Yes | Yes | |
| Inhaler air flow resistance testing (P1) | Yes | Yes | |
| Force/displacement measurements for inhaler actuation | Optional | Optional | Optional |
| Weighing of inhaler for determination of dose weight | No | Optional | Optional |
| Automated dose recovery | A Xelair® 1 series workstation is available for dose recovery and assay preparation. A number of sample output options are available | Yes, proven techniques are used to recover the dose from the collection chamber and form a homogenous solution | |
| Analytical standards |
| Yes, the solution can be configured to use internal and external standards | |
| Use of multiple reagents in single run |
| Yes, multi-reagent compatible. The type and capacity of reagent vessels can be specified by the client | |
| Sample presentation |
| Samples delivered to vials or well plates for transfer to analysis equipment. HPLC racks can be specified by the client | |
| HPLC integration |
| Optional, HPLC integration by automated vial transfer or direct injection methods. Data integration can be performed by XML file export or using the SDK supplied with a client’s chosen CDS. | |
| Automated equipment cleanup |
| Yes, automated cleanup of the collection chamber and all drug contact surfaces. | |
| Other integrations | Optional integrations e.g. run definitions from LIMs or run results to LIMs. Integrations are dependent on requirements e.g. XML file, CSV file, direct data connection such as ODBC. | ||
| Unattended 24 hour high throughput operation | No | No | Yes |
| 21 CFR Part 11 compliant software | Yes | Yes | Yes |
| Validation pack provided | Yes | Yes | Yes |